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Why scientists should take more coffee breaks
Grad students should make time for casual conversations with peers, this Ph.D. student writes
Defining precancer: a grand challenge for the cancer community
Nature Reviews Cancer – In this Expert Recommendation, Faupel-Badger and colleagues present a conceptual framework to define precancer and advance our understanding of the earliest…
Identifying metabolic limitations in the tumor microenvironment
Tools to identify metabolic stresses in tumors are improving the ability to find vulnerabilities of cancers.
Why scientists should take more coffee breaks
Grad students should make time for casual conversations with peers, this Ph.D. student writes
Botton-Champalimaud Pancreatic Cancer Centre Operational from September 30 | Champalimaud Foundation
The Botton-Champalimaud Pancreatic Cancer Centre, a cutting-edge facility dedicated to the treatment and research of pancreatic cancer, officially commenced all its surgical and inpatient activities…
Genderized Gut and Oral Microbiome Shifts: Uncovering Sex-Specific Dysbiosis in Pancreatic Cancer
Abstract: Background: Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest cancers, responsible for approximately 466,000 deaths globally in 2020. Its incidence increases by about…
DNA-sensing pathways in health, autoinflammatory and autoimmune diseases
Nature Immunology – In this Review, Fitzgerald and Dong summarize the fundamentals of DNA-sensing pathways in health, autoinflammatory and autoimmune diseases.
Intrinsic temperature increase drives lipid metabolism towards ferroptosis evasion and chemotherapy resistance in pancreatic cancer
Nature Communications – The development of cancer is typically accompanied by changes in the tumor microenvironment that support tumor growth and affect therapy response. Here,…
Integrative clinical and preclinical studies identify FerroTerminator1 as a potent therapeutic drug for MASH
Tao et al. discover that excess hepatic iron accelerates MASH progression primarily via c-Myc-Acsl4-triggered ferroptosis. Targeting hepatic iron overload and ferroptosis with FerroTerminator 1 (FOT1) reverses…
Seminar Clips: The Four Minute Mile Analogy- David Hong, MD | Stanford Cancer Institute
Clip taken from “Targeting RAS: The Past, Present, and the Future,” presented by David Hong, MD. To watch the entire seminar, please visit https://www.youtub…