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Successful Treatment of HIV-associated Kaposi’s Sarcoma with Immune Checkpoint Blockade
Kaposi’s sarcoma (KS) is an incurable, HIV-associated malignancy. We reviewed 320 immunotherapy-treated patient records. Seventeen had HIV-associated malignancies, including nine men with KS. Median viral…
Aland is lovely, weapon-free and too close to Russia
Finland worries the demilitarised islands could fall prey in a conflict
Policy Briefs With Personality: How to Innovatively Disseminate Evidence for Advocacy
Affiliations: Department of Family Medicine and Community Health, School of Medicine and Public Health, University of Wisconsin, Madison, WI Alison N. Huffstetler, MD – Robert…
Bat die-off led to more insecticide use and more infant deaths in US
In counties in the US affected by a bat-killing disease, there has been a 31 per cent increase in insecticide use and an 8 per…
ClinicalTrials.gov
Hide glossary Study record managers: refer to the Data Element Definitions if submitting registration or results information.
NOT-DK-24-026: Request for Information (RFI): Research Strategies for Addressing Obesity Heterogeneity
NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: Request for Information (RFI): Research Strategies for Addressing Obesity Heterogeneity NOT-DK-24-026. NIDDK
In vivo CAR T cells move into clinical trials
Nature Reviews Drug Discovery – Drug developers want to reprogramme immune cells directly in the body, opening up new gene therapy frontiers in cancer and…
PD-1 Blockade with Pembrolizumab in Advanced Merkel-Cell Carcinoma | NEJM
Merkel-cell carcinoma is an aggressive skin cancer that is linked to exposure to ultraviolet light and the Merkel-cell polyomavirus (MCPyV). Advanced Merkel-cell carcinoma often responds…
Office of Advocacy Relations
OAR brings the cancer advocacy and NCI communities together to help identify research opportunities that speed advances and improve patient outcomes.
Gene-environment interactions: ubiquitous yet undetectable
Polygenic models have revealed widespread GxE hiding under the surface of trait heritability