We evaluated the capability of soluble cardiac biomarkers to predict tolerability and outcomes of IMiD-containing treatments among 106 patients treated on clinical trials. Baseline elevations in troponin T (TnT) and N-terminal brain naturietic protein …
another transthyretin stabilizer, has very recently been FDA-approved following positive results in the ATTRibute-CM trial. Vutrisiran, a transthyretin gene silencer, demonstrated efficacy in the HELIOS-B…
This cohort study characterizes the clinical phenotype and natural history of asymptomatic patients with transthyretin cardiac amyloid infiltration.
A putative lipid binding site in the cytoplasmic domain of the human P2X4 receptor modulates the rate of desensitization.
Clinical. We are seeking a highly skilled and motivated cardiologist, specializing in the care of patients with Hypertrophic Cardiomyopathy and/or Cardiac Amyloidosis, within the Division…
A video from Ahmad Masri (as part of Cardiology 2024 Year in Review), posted on Dec 21, 2024.
AbstractBackground and Aims. The positron emission tomography (PET) tracer 18F-florbetaben is a promising diagnostic tool for light-chain cardiac amyloidos
A 63-year-old woman presents to the office for a second opinion on chronic chest pain and heart failure management. She has a medical history of…
Gurusher S. Panjrath, MBBS, FACC Barbara Wiggins, PharmD, FACC Megan Coylewright, MD, MPH, FACC, Ex Officio 2. Assumptions and Proposed Definitions 4 2.1. General Clinical…
Scientific Reports – Myocardial inflammatory cells in cardiac amyloidosis
Amyloid-specific antibodies have been shown to opsonize and enhance amyloid clearance in systemic amyloidosis mouse models. However, the immunological mechanisms by which amyloid is removed…
