Introduction: Chronic immune thrombocytopenia (cITP) is a common, acquired, autoimmune disorder resulting in abnormally low blood platelet counts (
Key Points. The inherited AnWj-negative blood group phenotype is caused by homozygosity for a deletion in MAL, encoding Myelin and lymphocyte proteinMal pr
Key PointsCAR-37 T cells expanded to >98% of T cells and led to complete responses but caused severe cytopenia associated with high levels of IL-18.Depl
In this issue of Blood, Mazziotta et al1 investigate CD8+ T-cell subpopulations as correlates with response to induction chemotherapy in acute myeloid leuk
In this issue of Blood, Sirenko et al1 report the prevalence of UBA1 mutations in 2 cohorts of patients with myelodysplastic syndrome (MDS) and demonstrate
Key Points. Combining CAR-T cells targeting CD19 & CD22 with a recombinant, polymer-conjugated IL15 receptor agonist (NKTR-255) was safe and feasible.2
In this issue of Blood, Elitzur et al1 investigate the outcomes of hematologic malignancies in individuals with ataxia-telangiectasia (A-T) by conducting a
Key PointsThe safety and efficacy benefits of ide-cel were proportionate in young and older patients despite frailty and geriatric characteristics.Treatmen
In this issue of Blood, Mazziotta et al1 investigate CD8+ T-cell subpopulations as correlates with response to induction chemotherapy in acute myeloid leuk
Key PointsThe presence of CLL cells delays T-cell receptor–mediated CAR T-cell activation and impairs proliferation and restimulation.Blocking CD24 and CD5
Abstract. T-cell engaging–therapies have transformed the treatment landscape of relapsed and refractory B-cell non-Hodgkin lymphomas by offering highly eff
