Quickly and accurately identifying facial expressions plays an important role in social interactions. Song et al., (2022) investigated the influence of emotional contextual information (fearful, happy, and neutral scenes) on the neural processing of fearful expressions during the early stages of facial recognition based on the face-specific N170 component derived from the event-related potential (ERP) method. Their findings suggest that people allocate more attention to the processing of facial information when the valence between emotional context and expression conflicts.Although extensive research has focused on the detection of uncertain threat signals in anxious individuals, little has been done to investigate the detection of uncertain safety signals in people with anxiety. Jin et al., (2022) compared 16 subjects with high trait anxiety and 16 with low trait anxiety during a modified cue-target task in certain and uncertain stimulus blocks based on the ERP components P2 and N2 th

Peripheral nerve injury often results in poor functional recovery due to a prolonged period of muscle denervation. In particular, absent axonal contact, denervated muscle can undergo irrevocable atrophy and diminished receptiveness for reinnervation over time, ultimately reducing the likelihood for meaningful neuromuscular recovery. While innovative surgical approaches can minimize the harmful effects of denervation by re-routing neighboring—otherwise uninjured—axons, there are no clinically-available approaches to preserve the reinnervation capacity of denervated muscles. Blocking intramuscular connexin hemichannel formation has been reported to improve muscle innervation in vitro and prevent atrophy in vivo. Therefore, the current study investigated the effects of orally administered boldine, a connexin hemichannel inhibitor, on denervated-related muscle changes and nerve regeneration in a rat model of delayed peripheral nerve repair. We found that daily boldine administration signif