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Centers for Disease Control and Preve...COVID-19 Vaccination - 16 hours
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Latest Headlines
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NatureMolecular states during acute COVID-19 reveal distinct etiologies of long-term sequelae – Nature Medicine - 20 hours
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Transcriptomic analyses of acute phase whole blood from a large cohort of patients with COVID-19 identify molecular determinants of post-infection long-term...
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12/ GENES: Why do some get Long COVID & others don’t? We’re learning that different patterns of gene expression in acute COVID predict symptom patterns 1-yr later This study establishes a connection between acute & long COVID based on gene responses https://t.co/nxupgFhRmc https://t.co/nxupgFhRmc - view on twitter
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medRxivIncident autoimmune diseases in association with a SARS-CoV-2 infection: A matched cohort study - 20 hours
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Objectives To investigate whether the risk of developing an incident autoimmune disease is increased in patients with previous COVID-19 disease compared to people without...
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15/ Auto-Immune Diseases like Lupus wreak havoc 🧠 This well-done study of 640k pts w PCR-proven COVID vs. 1.9M controls prior to vaccines (Dec 2020) found lots of Autoimmune Dz 15 mos later. 42% new diagnoses of Graves, Sjogrens, Rheum Arthritis https://t.co/4Xew6geraA https://t.co/4Xew6geraA - view on twitter
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BioMed CentralObjective COVID-19 (SARS-CoV-2) has been associated with neurological sequelae even in those patients with mild respiratory symptoms. Patients experiencing cognitive symptoms such as “brain...
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7/ The exact cause of brain disease in #LongCOVID is unknown. Damaged executive function occurs in many. Why? This small study found much less Cortical Gray Matter 🧠 than expected on MRI, which complements large, controlled UK Biobank data (next tweet) https://t.co/qISTRyPlIV https://t.co/qISTRyPlIV - view on twitter
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#longcovid
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PubMedThe cerebral network of COVID-19-related encephalopathy: a longitudinal voxel-based 18F-FDG-PET study – PubMed - 20 hours
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The implication of this widespread network could be the neural substrate of clinical features observed in patients with COVID-19, such as frontal lobe syndrome,...
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9/ Some people actually lose cortical gray matter, which is made up on trillions of neurons. This is supported by multiple PET studies showing impaired frontal lobe hypo-metabolism at 6 months. Here’s one: https://t.co/Wd1u1ZWiio https://t.co/Wd1u1ZWiio - view on twitter
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NatureSevere COVID could cause markers of old age in the brain - 20 hours
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Key genes that are active in the brains of older people are also active in the brains of people who developed serious...
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13/ Does Severe COVID accelerate aging⁉️ Authors: “genes associated w inflammation & stress were ⬆️ active in brains of people after COVID than controls Conversely, genes linked to cognition & formation of connections between brain cells were ⬇️ active” https://t.co/39lGuXGvUW - view on twitter
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The IndependentMajority of people with long Covid ‘report experiencing some form of stigma’ - 20 hours
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An estimated 2.1 million people are living with long Covid in the...
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21/ Avoid stigmatizing Long COVID patients Researchers @NisreenAlwan found 95% of sufferers experience stigma & 76% experience it “often” or “always” – even more often w formal diagnosis. Instead of denial & frustration, let’s explore ideas & solutions? https://t.co/B4u88iYfVt - view on twitter
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European Respiratory SocietyCirculating anti-nuclear autoantibodies in COVID-19 survivors predict long-COVID symptoms - 20 hours
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Background Autoimmunity has been reported in patients with severe COVID-19. We investigated whether antinuclear/extractable-nuclear antibodies (ANAs) were present up to a year after infection,...
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16/ The family of autoimmune diseases found in COVID survivors most often involved blood vessels Fitting since COVID is a disease of blood vessels Others are finding that persistent anti-nuclear antibodies (think Lupus) predict #LongCOVID https://t.co/Mo4b1IFTOp https://t.co/Mo4b1IFTOp - view on twitter
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www.niaid.nih.govNIAID Pandemic Autopsy Study Fosters Long COVID Treatment Trial - 20 hours
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A COVID-19 autopsy study from NIAID and many other collaborators helped researchers rethink where SARS-CoV-2 spread in the body and how long its remnants...
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5/ Stein’s @Nature autopsy study (tw#4👆) sparked upcoming Paxlovid clinical trials Authors: “We provide the most comprehensive analysis of cellular tropism, quantification & persistence of SARS-CoV-2 across the human body including the brain.” Tropism? https://t.co/joPy1WyBpS https://t.co/joPy1WyBpS - view on twitter
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NatureManthiram and colleagues analyze the peripheral blood, tonsils and adenoids in children undergoing tonsillectomy or adenoidectomy and find evidence of continued tissue-specific immunity to...
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14/ Persistent Immunity can be a Double-Edged Sword In some it means #Recovery In others? These authors conclude that in some kids, activated cells in tonsillectomy tissue after COVID may lead to long-COVID & multisystem inflammatory syndrome https://t.co/QJipo21AZO https://t.co/QJipo21AZO - view on twitter
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COVID-19 vaccines protect against COVID-19. Get safety info and...
Myocarditis after #COVID19 vaccination is rare. Heart problems are 5 times more likely after COVID-19 illness than after COVID-19 vaccination. Learn more: https://t.co/vB5hxYukU1. https://t.co/vB5hxYukU1. - view on twitter