Both Fallopian Tube and Ovarian Surface Epithelium Are Cells-Of-Origin for High-Grade Serous Ovarian Carcinoma – PubMed

The cell-of-origin of high grade serous ovarian carcinoma (HGSOC) remains controversial, with fallopian tube epithelium (FTE) and ovarian surface epithelium (OSE) both considered candidates. Here, by using genetically engineered mouse models and organoids, we assessed the tumor-forming properties of …

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