The health and economic impact of multidrug-resistant (MDR) bacteria has continuously grown over the past years, reaching an estimated peak of approximately 700 000 attributable deaths per year.1 Neglected hygiene, poor compliance with infection control procedures, inappropriate antimicrobial use, and insufficient availability of diagnostics and new effective antibiotics have contributed to this…
The deployment of the RTS,S/AS01 vaccine and the prequalification of R21/Matrix-M vaccine are important milestones that target child health and survival, especially in Africa.1 Sub-Saharan…
RH5.1/Matrix-M appears safe and highly immunogenic in African children and shows promising efficacy against clinical malaria when given in a delayed third-dose regimen. This trial…
The publication of a phase 3 trial by Terry Nolan and colleagues in The Lancet Infectious Diseases marks a key step towards licensing a new…
This study demonstrates breadth of immune response against a panel of 110 MenB strains for the MenB component of the investigational MenABCWY vaccine, when administered…
Tuberculosis remains a public health concern, and electronic monitors show promise in improving treatment adherence and health outcomes among patients with tuberculosis. This Review aims…
Peruse the current issue of The Lancet Infectious Diseases, a monthly journal covering international issues relevant to clinical infectious diseases specialists worldwide
For the first time in 60 years, the tuberculosis drug development pipeline promises novel drugs and treatment strategies for safe, well tolerated, highly efficacious, and…
In this 14-day trial, quabodepistat plus delamanid plus bedaquiline, a novel three-drug combination, appeared to be safe, well tolerated, and provided robust early bactericidal activity…
We did a systematic review and meta-analysis of trials of treatment for rifampicin-susceptible tuberculosis to evaluate the representativeness of participants compared with characteristics of the…
The COVID-19 pandemic reminded us of what vaccines can do to prevent life-threatening diseases.1 Respiratory infections such as influenza, COVID-19, respiratory syncytial virus (RSV), and…
