Antiresorptive and anabolic agents in the prevention and reversal of bone fragility

Bone turnover and risk of fracture are orchestrated by homeostatic functions of osteoclast–osteoblast bone remodelling units. Anabolic and antiresorptive drugs used to treat and prevent fractures have differing effects on remodelling defects, but which class of drug is the preferred front-line therapy?

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