An Expiration Date for Etomidate?
Endotracheal intubation to facilitate invasive mechanical ventilation in critically ill patients is a high-risk procedure. For example, cardiovascular instability occurred in nearly 40% of intubations in critically ill patients included in the recent INTUBE study (International Observational Study to Understand the Impact and Best Practices of Airway Management in Critically Ill Patients), which in turn was associated with higher risks of mortality (1). Given this particularly high-risk nature of endotrach