Zhang et al. demonstrate that fear extinction memory requires new engram cells to be formed and stored in BLA neurons that drive reward behaviors. Fear extinction engram cells and reward-responsive cells are functionally equivalent in driving reward behaviors and fear extinction. Fear extinction memory is a newly formed reward memory.
In neuroscience, the search for the causes of behavior is often just taken to be the search for neural mechanisms. This view typically involves three…
Mechanism is a common and powerful concept, invoked in grant calls and publication guidelines. But scientists use it in different ways, making it difficult to…
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Shop Award Winning Fine Art Landscape Photographer by JohnCrowleyPhoto located in Bantry, Ireland.
In this narrative historical review, I want to take a closer look at the concept of perceptual similarity both as it applies within, and between,…
1 Cold Spring Harbor Laboratory, Neuroscience Program, Cold Spring Harbor, NY, USA 2 Department of Biological Sciences, Columbia University, New York, NY, USA 3 Howard…
A new study shines light on a hotly contested centuries-old mystery.
Across species, navigation is crucial for finding both resources and shelter. In vertebrates, the hippocampus supports memory-guided goal-directed navigation, whereas in arthropods the central complex…
The algorithm needs a little help to find the global energy minimum
Tony Zador is a Computational Neuroscientist from the Cold Harbour Springs Laboratory who is attempting the gargantuan task of modelling all the connections …
