A white-knuckle ride of open COVID drug discovery
In early 2020, a spontaneous global collaboration came together to design a new, urgent antiviral treatment. There are lessons in what happened next.
In early 2020, a spontaneous global collaboration came together to design a new, urgent antiviral treatment. There are lessons in what happened next.
Nature – Viruses known as bacteriophages are difficult to study, but they are beginning to give up their secrets.
Pediatric Research – Impact of probiotics on gut microbiome of extremely preterm or extremely low birthweight infants
Cellular & Molecular Immunology – Kynurenine-AhR reduces T-cell infiltration and induces a delayed T-cell immune response by suppressing the STAT1-CXCL9/CXCL10 axis in tuberculosis
Nature Communications – Gene drives have the potential to support malaria control by suppressing vector populations, but their impacts will depend on local ecology and…
Nature Reviews Microbiology – In this Perspective, Joos, Ross and colleagues reflect on current approaches and the challenges of defining a ‘healthy’ microbiome, and propose…
In several B cell malignancies, BTK is a crucial mediator of oncogenic signalling pathways and inhibitors of this kinase have substantially improved patient outcomes. This…
Nature Communications – In this work, authors assess airway microbiome dynamics to show bacterial pneumonia in critically ill COVID-19 patients is significantly associated with death,…
In this Perspective, the authors discuss how our understanding of coeliac disease could provide insights into the mechanisms of multiple sclerosis, the involvement of Epstein–Barr…
Nature Cancer – Snyder and colleagues present a comprehensive multiomic atlas of normal mucosal, benign polyps and dysplastic polyps from six persons with familial adenomatous…
Nature Communications – Effective surveillance of respiratory virus particles in air requires highly sensitive tools that can produce timely and accurate results. Here, the authors…