The opinions expressed in this article are not necessarily those of the editors or of the American Heart Association.Presented in part at the Clinical-Pathological Conference chaired by Anna F. Dominiczak and Rhian Touyz at the virtual Hypertension Scientific Sessions 2021, September 28, 2021. Jing Chen, Xin Chen, and Ji-Guang Wang presented the case and led the discussion.For Sources of Funding…
BACKGROUND: The mechanisms by which salt increases blood pressure in people with salt sensitivity remain unclear. Our previous studies found that high sodium enters antigen-presenting…
BACKGROUND: The mechanisms by which salt increases blood pressure in people with salt sensitivity remain unclear. Our previous studies found that high sodium enters antigen-presenting…
Hypertension is one of the most commonly treated conditions in modern medical practice, but despite its long history, it was largely ignored until the midpoint…
BACKGROUND: Primary aldosteronism (PA) is frequently caused by a unilateral aldosterone-producing adenoma with a PA-driver mutation. Unilateral adrenalectomy has a high probability of short-term bioc
Correspondence to: Matthew R. Alexander, Department of Medicine, Division of Clinical Pharmacology, Vanderbilt University Medical Center, 2215 Garland Ave, 560B RRB, Nashville, TN 37232. Email…
BACKGROUND: High circulating DPP3 (dipeptidyl peptidase 3) has been associated with poor prognosis in critically ill patients with circulatory failure. In such situation, DPP3 could…
Background: We tested the hypothesis that patients with heart failure with preserved ejection fraction (HFpEF) would have greater muscle sympathetic nerve activity (MSNA) at rest…
Renin was discovered more than a century ago. Since then, the functions of the renin–angiotensin system in the kidney have been the focus of intensive…
BACKGROUND: Gray matter (GM) and white matter (WM) impairments are both associated with raised blood pressure (BP), although whether elevated BP is differentially associated with…
BACKGROUND: The extent to which a history of hypertensive disorders of pregnancy is associated with incident cardiovascular disease also among women with diabetes is unknown.…
