A randomized controlled trial to isolate the effects of fasting and energy restriction on weight loss and metabolic health in lean adults

Intermittent fasting is increasingly popular, but whether fasting itself offers specific nutritional benefits in lean individuals compared to traditional daily calorie restriction is unknown. In a small clinical trial of healthy individuals, Templeman et al. found that alternate-day fasting without energy restriction was ineffective at reducing body mass. Even with net energy intake restricted to…

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