β-Blocker Use and Delayed Onset and Progression of Huntington Disease
This study evaluates the impact of β-blockers on the timing of motor diagnosis onset and progression of Huntington disease symptoms.
Related Articles
High-Risk Opioid Prescribing and Nurse Practitioner Independence
This difference-in-differences analysis examines whether the rates of high-risk opioid prescribing changed in association with nurse practitioner independence legislation.
Necrotic Plaque in a Patient With Malignant Hematologic Disease
A man in his 70s with myelodysplastic syndrome presented with a painful violaceous eruption on his left lower leg accompanied by low-grade fever and fatigue…
Government Funding for the Development of Enzalutamide
This cross-sectional study assesses the various patents and US government grants that were critical to the publicly funded development of the cancer drug enzalutamide.
Bilateral Retinal Nerve Fiber Layer Thickening in a Middle-Aged Woman
A middle-aged Hispanic woman presented for evaluation of an asymptomatic epiretinal membrane in the left eye. She had an ocular history of amblyopia in the…
Association of Vascular Risk With Severe vs Non-Severe Stroke | Neurology
Background and ObjectivesAcute stroke is associated with a spectrum of functional deficits. The objective of this analysis was to explore whether the importance of individual…
Spatial transcriptomic clocks reveal cell proximity effects in brain ageing
Nature – A spatially resolved single-cell transcriptomics map of the mouse brain at different ages reveals signatures of ageing, rejuvenation and disease, including ageing effects…
Zerlasiran—A Small-Interfering RNA Targeting Lipoprotein(a)
This phase 2 randomized clinical trial evaluates the optimal dose, dosing interval, and safety of zerlasiran, a small-interfering RNA targeting hepatic synthesis of apolipoprotein(a), to…
Frontiers | Calcium-sensor proteins but not bicarbonate ion activate retinal photoreceptor membrane guanylyl cyclase in photoreceptors
1 Pennsylvania College of Optometry, Salus at Drexel University, Elkins Park, PA, United States 2 Department of Neurobiology and Anatomy, Drexel University, Philadelphia, PA, United…
Feasibility of Simon 2-Stage Futility Trials in Early Parkinson Disease | Neurology
Background and ObjectivesDisease-modifying treatments (DMTs) are a major unmet need in Parkinson disease (PD). To date, trials investigating DMT candidates in PD most often used…
ILAE Eastern Mediterranean & Africa webinaire (français) // International League Against Epilepsy
Contact Information ILAE Headquarters 1747 Pennsylvania Ave. NW Suite 1000 Washington, D.C. 20006,
